Grade 2 endometrioid carcinoma is still relatively serious, and if the disease progresses further, it will jeopardize the life span of patients. Endometrioid carcinoma belongs to a group of epithelial malignant tumors occurring in the endometrium, and these patients will have vaginal bleeding, menstrual disorders and other related symptoms, especially in perimenopausal or postmenopausal women. This disease is mainly related to excessive stimulation of endometrium by estrogen, and obesity, diabetes, hypertension, infertility, ovarian diseases, etc., are all high-risk factors for the occurrence of endometrial cancer, so patients should pay great attention to early detection and early treatment. For the treatment of this disease, surgery is the main treatment at present, and at the same time, radiotherapy and targeted therapy need to be assisted to improve the prognosis of patients.