There is no uniform consensus on the indications for postoperative anticoagulation of varicose saphenous veins, and the occurrence of postoperative thrombosis is less related to whether or not to anticoagulate and more related to whether or not to get out of bed early. In principle, it is recommended for people with high risk of deep vein thrombosis to get out of bed at an early stage, and to be treated with compression stockings, and anticoagulation should be considered only after weighing the advantages and disadvantages of anticoagulant therapy: 1. Whether the patient has thrombotic risk factors, patients can be assessed for thromboembolic risk, as long as located in the risk of intermediate risk or above should be postoperative anticoagulation, such as obesity, tumors, renal disease, rheumatoid immune disease, previous thrombotic disease, and so on. 2. The risk of postoperative thrombosis is increased in those with thrombosed superficial phlebitis. 3. The risk of thrombosis is significantly increased in simultaneous surgery of both lower limbs, which should be routinely anticoagulated. 4. Combined iliac vein compression syndrome, which is an independent thrombotic risk, should be treated first and routinely anticoagulated after surgery. 5. Those who have elevated D-dimer before surgery and exclude other diseases that cause elevated D-dimer should be routinely anticoagulated after surgery, and dynamic testing of D-dimer levels is required. Common anticoagulant drugs include warfarin, heparin, etc. However, anticoagulant therapy should be used with caution for people with obvious bleeding tendency, severe liver and kidney dysfunction, etc. In the course of treatment, the coagulation function should be monitored regularly according to the doctor’s instructions, and timely consultation is required in case of any discomfort.