The reason you should not take oral azithromycin for more than 3 days is that continued use can lead to a buildup of the drug, making the side effects of the drug worse. Azithromycin oral absorption is fast, can be widely distributed in the blood tissue, but the plasma protein binding rate is low, its half-life can be up to 35~48 hours, if you continue to take azithromycin, the drug can continue to accumulate, nausea, vomiting, diarrhea, rash and other adverse reactions. If there are abnormalities in liver and renal function, etc., the condition may be aggravated and death may occur. Azithromycin is a semi-synthetic 15 yuan macrolide antibiotic, mainly used for the treatment of acute pharyngitis, acute tonsillitis, acute and chronic bronchitis attacks caused by purulent streptococcus. It is contraindicated in patients who are allergic to azithromycin, erythromycin, other macrolide antibiotics, or any excipients. It is recommended to use the drug under medical supervision.