Artificial liver usually lives for about 6 to 12 months. Artificial liver is mostly used in clinical practice for patients with liver failure to remove excessive bilirubin and toxins from the blood, but it cannot replace all the functions of the liver, which has very many functions, contents and so on. The human liver has many functions such as digestion, metabolism, detoxification, immunity, hemostasis and so on. If patients use artificial liver for a long period of time, it will produce many life-threatening and serious complications, such as hepatic encephalopathy, hemorrhage, recurrent infections and so on. Artificial liver is a short-term alternative treatment measure before liver transplantation for patients with liver failure. It is recommended that patients should be matched as early as possible to find a matching liver source and undergo liver transplantation for treatment to fundamentally replace the liver that has already failed, which can greatly prolong the patient’s survival period.