A burst of stabbing pain below the left side of the ribs may be associated with intercostal neuralgia, herpes zoster, angina pectoris, as well as pleurisy, urinary stones and other diseases. 1. Intercostal neuralgia is due to a variety of reasons induced by the nerve damage, the main clinical manifestation of paroxysmal or persistent pain, the cause of its onset may be related to tumors, infections and other factors 2. Herpes zoster is a skin disease caused by the infection of varicella zoster virus, due to the virus will damage the nerves, so it will cause neuralgia in the clinic, which is manifested as burning or tingling discomfort in the local skin. 3. angina pectoris is due to coronary artery vasospasm or stenosis and lead to acute myocardial blood supply insufficiency, the main clinical manifestation of the left anterior region of the heart pain, but also can be manifested as the pressure of the sternum, but also can be radiated to the left upper limb. 4. Pleurisy is an inflammatory lesion occurring in the pleural cavity, which can be manifested as stabbing pain, and the pain will be significantly aggravated by pulling when coughing and deep breathing. 5. The pain caused by the left ureteral stone is due to the stone obstruction in the ureter and induced a kind of colic, the patient can be manifested as the left side of the waist and abdomen pain. As pain is a subjective feeling, the specific etiology needs to be analyzed by a doctor’s interview and combined with other clinical manifestations.