Nifurtimox is a drug commonly used in clinical practice to inhibit the growth of mycobacteria and is commonly used in the treatment of mycosis fungoides. During the treatment of mycosis fungoides, it is necessary to pay attention to the change of vaginal discharge and the symptoms of vaginal itching. Generally, treatment is given for one week and discontinued at the end of the course of treatment. After discontinuation, patients are advised to visit the local hospital again to have their vaginal discharge examined. For patients who are not completely cured, a second course of treatment may be considered. For complicated mycotic vaginitis, six months of consolidation therapy may be considered to improve the effectiveness of the medication.