A high-risk HPV positive indicates an infection with the human papillomavirus, which is high-risk. There are high-risk and low-risk HPV infections, and high-risk infections are susceptible to cervical cancer. This is one of the screening tests for cervical cancer, and it also includes a TCT test, which is a liquid-based cytology of the cervix. If there is also a problem with the liquid-based cytology, the next step must be a colposcopy, and the next step in treatment will be determined based on the results of the colposcopy. If the HPV is purely high risk positive, being types 16 and 18, colposcopy is required regardless of whether the cervical cytology has precancerous lesions or not. Because these 2 types, which are the more severely infected viruses, are also the ones most likely to cause precancerous changes in the cervix, it is important to have a close watch.