Hydrochlorothiazide tablets and perindopril tert-butylamine tablets combined can treat edema, hypertension, congestive heart failure caused by chronic nephritis. Chronic nephritis is mainly manifested as hematuria, proteinuria, hypertension, edema and so on. Hydrochlorothiazide tablets belong to diuretics, which are mainly used in the treatment of edematous diseases. Perindopril tert-butylamine tablets are mainly used in the treatment of hypertension and congestive heart failure. Therefore, the combination of hydrochlorothiazide tablets and perindopril tert-butylamine tablets can effectively reduce blood pressure, reduce edema and heart failure caused by severe edema. Adverse reactions such as dry mouth, muscle cramps, nausea and vomiting may occur when taking hydrochlorothiazide tablets, and those who are allergic to this product should be prohibited from using it. Adverse reactions such as headache, dizziness, abdominal pain and diarrhea may occur with perindopril tert-butylamine tablets, and should be contraindicated in those who are allergic to the product, those with a history of angioneurotic edema associated with the use of ACE inhibitors, and those who are pregnant or breastfeeding. Both hydrochlorothiazide tablets and perindopril tert-butylamine tablets need to be used under the guidance of a doctor, and should not be used blindly on their own to avoid adverse effects.