Prickly heat in children is mainly caused by high heat environment that leads to sweat blocking the sweat ducts, and there is no quick cure. General treatment and medication can be used to intervene according to the child’s condition. 1. General treatment: wear loose clothes to reduce the friction between the clothes and the affected area; keep the affected area clean and dry, avoid the application of irritating shower gel and other toiletries; eat a light diet, avoid spicy and stimulating diet; keep the room ventilated and cool, avoid prolonged exposure to hot and humid environments; apply ice packs to the affected area to relieve the itching and other uncomfortable symptoms. 2. Medication: (1) Topical medication: patients can follow the doctor’s instructions for external use of glycerite lotion, prickly heat powder for young children and other drugs for treatment. After the use of medication, tingling, redness, swelling and other adverse reactions, the drug should be discontinued, and timely medical treatment. (2) oral drugs: for patients with obvious itching, can also be combined with cetirizine and other drugs for treatment; patients with co-infection, according to the pathogen application of azithromycin and other drugs for treatment. After the use of drugs, nausea, abdominal pain and other adverse reactions, should also be timely medical treatment. Children with prickly heat should go to the dermatology department of the hospital and be treated by a specialist doctor to develop a treatment plan. The medication should be used as prescribed by the doctor.