The treatment of breast nodule 1.77 cm should be traced back to the history of breast disease, improve the imaging examination, pathology results and other methods to clarify the nature of the nodule, surgical treatment, drug treatment, regular monitoring. 1. Surgical treatment: generally patients with breast nodules should know whether there is a family history of breast cancer, if there is a family history of breast cancer, the breast nodule is significantly larger than before, and the nature of the nodule should be clarified as soon as possible, and if it is breast cancer, it is necessary to carry out radical surgery, and according to the metastasis or not, and the physical quality of the body to decide whether to radiotherapy or targeted therapy, endocrine therapy. 2. Drug treatment: Generally, benign nodules can be treated with oral Xiaojin Wan and Lactofetish Pill; if it is breast cancer, some of the patients with immunohistochemistry results suggesting estrogen and progesterone positivity need to take Letrozole tablets and Tamoxifen tablets orally to carry out endocrine therapy; if it suggests that the patients with HER2+ can use trastuzumab or patuxinumab for targeted anticancer therapy. 3. Regular monitoring: if the breast ultrasound or molybdenum target examination of the third grade, suggests that this nodule is benign, nodule demarcation is clear peripheral no blood flow, no nodule calcification, no special treatment; the second grade of nodules will generally have a high likelihood of benign; and first grade of nodules suggests that there is a high likelihood of breast cancer, need to be timely puncture pathology to clarify the need for resection if necessary. Breast nodules 1.77 cm, usually need to be combined with specific nodule performance to develop appropriate treatment options, found that breast nodules, should be as soon as possible to go to the breast specialist clinic to clarify the nature of the nodules, to avoid aggravation of the condition of the drug treatment timing.