Chromosome 14 trisomy is not necessarily caused by the inheritance of chromosomal abnormalities from the parents. There are many reasons for the formation of chromosome 14 trisomy in an embryo, including abnormal inheritance of chromosomes from the parents, new mutations during embryonic development, and exposure to excessive amounts of radioactive substances or teratogenic drugs. The combination of sperm originating from the father and egg originating from the mother to form an embryo recombines three or only one chromosome of chromosome 14, resulting in developmental malformations after chromosomal abnormalities in the fetus. Certain genetic mutations in the fetus during development can also result in trisomy of chromosome 14. In addition, chromosomal abnormalities can also be caused by exposure to excessive amounts of radioactive substances or teratogenic drugs during pregnancy. It is recommended that both spouses go to the hospital for a pre-pregnancy eugenics health checkup to assess whether their bodies are suitable for pregnancy; quit smoking and drinking, develop good habits, and don’t stay up late. Moderate exercise to maintain good health, to avoid prolonged exposure to radiation or pollution in the environment, to get out of the toxic and harmful work environment; to maintain a happy mood; avoid heavy physical labor.