Usually, most patients with insulin resistance have metabolic disorders, such as obesity, abnormal blood pressure, acanthosis nigricans, etc., and some patients have no obvious symptoms. Insulin resistance refers to the decreased efficiency of insulin in promoting glucose uptake and utilization due to various reasons, and most patients with insulin resistance have metabolic disorders. For example, hyperglycemia and hypertension, hyperuricemia, fatty liver and obesity. Insulin resistance is involved in the development of these diseases to a certain extent. Most of the patients with insulin resistance have obesity and less exercise, it is recommended that patients with insulin resistance should exercise more and control their weight, which can usually improve insulin resistance to a certain extent. Clinically, biguanides can improve insulin resistance to a certain extent. Patients with insulin resistance are advised to consult an endocrinologist for treatment under the guidance of a doctor.