Aging is a symptom of Hutchinson-Gilford Syndrome, also known as childhood progeria, a genetic disease first reported by Hutchinson in 1886. Progeria patients’ body aging process is 5 to 10 times faster than normal, the patient looks like an old man, the organs also quickly decline, resulting in a decline in physiological functions. Signs include thinness, hair loss and late teething. Children with this rare disease can look as if they are in their 60s or 70s, even though they are only 16 years old. Most of them die from diseases of aging, such as cardiovascular disease, for which there is no effective treatment, but only medication. Although the disease is a congenital disorder, it is not certain whether it is autosomal recessive or dominant. The disease is a syndrome characterized by delayed development and progressive age-related degenerative changes that occur in infancy. Researchers at the Progeria Research Foundation announced on June 17, 2004, that mutations in the LaminA gene are responsible for the progressive degeneration of cell structure and function in children with progeria. The full name of progeria is Hutchinson-Gilford progeria syndrome (HGPS or Progeria). The study was published in the mid-June issue of ProceedingsoftheNationalAcademyofSciences (PNAS). Progeria is a rare, fatal genetic disorder in which patients age rapidly from the same age. The study focuses on the importance of the LaminA gene for the maintenance of cell structure and function, which encodes a protein that scaffolds cell structure and is involved in gene expression and DNA replication. This study suggests that mutations in the LaminA gene are associated with cellular aging in progeria, possibly due to mutations in cellular function caused by the LaminA protein, and that instability of the cellular nuclear membrane plays a key role in Hutchinson-Gilford progeria syndrome. The results of this study have also led scientists to further understand the heart disease and cellular aging that occur in progeria. Progeria occurs in about one to four out of every eight million births.