Elevated d2 polymer after thrombolysis in pulmonary embolism is caused by the role of the body’s fibrinolytic system and coagulation function, indicating that the thrombolytic effect is good, usually after the operation will be elevated, and after a certain period of time will gradually decrease, but patients with persistent elevation need to be diagnosed immediately. Elevated d2 polymers can be used as a monitoring indicator after thrombolysis in pulmonary embolism, which will decrease after a short period of elevation, reflecting the therapeutic effect of thrombolysis. But for persistent d2 polymer elevation need to consider other diseases, may also exist in other parts of the thrombus, acute infarction, renal disease, etc., need to improve the relevant examination in a timely manner, and actively find the cause of the disease, to avoid the deterioration of other primary disease life-threatening. After pulmonary embolism d2 polymer persistent elevation need to timely consult a doctor, improve the relevant examination, identify the cause of the disease, to avoid further deterioration of the situation.