Sodium vitrate is a kind of hyaluronic acid secreted by the normal human body. The role of sodium vitrate is the role of hyaluronic acid, as follows: 1) protection of joint cartilage; 2) reduction of friction between joint cartilage; 3) anti-inflammatory effect. Sodium vitreous acid injection can reduce the friction between joint cartilage, anti-inflammatory, analgesic and improve the patient’s symptoms. The symptoms of degenerative knee osteoarthritis are swelling, pain, dysfunction and deformity. After the injection of sodium hyaluronate, the patient’s knee symptoms can be improved to some extent. The effect of sodium hyaluronate injection is slow and should be combined with other drugs. Patients with severe pain should take oral non-steroidal anti-inflammatory drugs, combined with physical function exercise and a whole set of knee treatment methods combined to improve knee function and achieve relief of knee pain and swelling.