Hookworm dermatitis caused by human hookworms and larvae of fecal nematodes is similar to cutaneous helminth migrans and is not easily differentiated, so the differential diagnosis between the two needs to be strengthened in clinical practice. Hookworm eggs can be found in the feces soon after the dermatitis has subsided. In contrast, fecal nematodes not only have skin damage, but also have rapid larval movement and intestinal symptoms, which can also be confirmed by fecal examination. Differential diagnosis: Hookworm dermatitis: When the filarial larvae of the Brazilian hookworm burrow into human skin, they cause skin damage, initially as erythema, which rapidly evolves into linear elevations and herpes with mild edema. Intense itching is caused by the movement of the larvae and tissue reaction. Bacterial infections are triggered by scratching, and may be accompanied by systemic symptoms such as swollen lymph nodes, fever, loss of appetite, and urticaria. It is also associated with eosinophilia and increased IgE levels in the blood. The duration of the disease may last for several weeks. The inflammation gradually subsides and dries and crusts over the area crossed by the worm. Skin lesions are most often seen in areas that are in frequent contact with soil, such as the hands and feet. In addition, they also occur on the buttocks, arms, legs and trunk. Cutaneous helminth migrations: Cutaneous helminth migrations caused by Schistosoma capsulatum larvae, Echinococcus nematodes larvae and Mannheimer’s cestode larvae are often found deep in the skin or in the muscular layer as mobile subcutaneous masses. The local skin surface is normal or slightly red and edematous, and pain is often inconspicuous, with some itching, burning or stinging. The masses appear intermittently at different sites. It is often complicated by visceral helminth migrans, with clinical manifestations of visceral organs affected by Sun, and obvious systemic reactions, such as fever, urticaria blood eosinophilia, malaise, muscle aches and loss of appetite. Caecal larvae dermatitis caused by the animal schistosome caecilians, the symptoms are mild when first infected, but can sensitize the body, so the symptoms increase when re-infected, with rash, herpes and edema, accompanied by strange itching or lymphatic vessels and lymph nodes involved due to stimulation of infection. The caecal larvae do not persist in the skin and are generally not lethal in the dermis, dying after a few days. However, the resulting local lesions can last up to two weeks before crusting off and healing.