There are six grades of pathological cytologic diagnosis of thyroid nodules, and the treatment plan for each case is different. 1. Grade I: not diagnostic, may not be diagnostic because of fewer epithelial cells, etc. Repeated sampling and testing is recommended. 2. Grade II: benign lesion, malignant risk 0-3%, clinical follow-up is recommended. 3. Grade III: atypical cellular or follicular lesions of unknown significance, with a malignant risk of 10% to 30%. Repeated fine needle aspiration biopsy of the thyroid gland, or molecular testing, or surgical treatment is recommended. 4. Grade IV: follicular tumor/suspected follicular tumor: malignant risk 25%～40%, molecular testing or surgical treatment is recommended. 5. Grade V: Suspected malignancy, malignancy risk 50%～75%, surgical treatment is required. 6. Grade VI: malignant, malignant risk 97-99%, requires surgical treatment. Thyroid nodules are recommended to be analyzed and treated in thyroid surgery or head and neck surgery of regular hospitals.