Anti-inflammatory drugs are antibiotics. How long it takes for an antibiotic to be metabolized depends mainly on the half-life of the drug. Five times the half-life of the drug, as a basic metabolism clean a standard, at this time basically no pharmacological effect, but there will still be a small amount of anti-inflammatory drugs in the body to remain, is not absolutely metabolized clean. Different anti-inflammatory drugs have different half-life, take ceftriaxone as an example, its half-life is about 8h, 5 half-life is about 40h time, that is about 3 days time. The application of ceftriaxone is injected once a day, anti-inflammatory drugs can manage the time is about 24h, 2 days application of ceftriaxone, is not to achieve the corresponding effect. And if it is to avoid this drug to cause disulfiram-like reaction, it is recommended that the time is longer, usually it is recommended to drink alcohol after a week, in order not to have disulfiram-like reaction. For penicillin, its half-life is also due to the body’s functional state, is about 30 minutes, 5 half-life is about 2.5h, penicillin to play a role in the effect of the day is a number of injections, it may be necessary to 6h or 8h injection. For benzylpenicillin to be injected intramuscularly, it can be injected once a week, which means that the corresponding effect of the drug can last for more than a week.