Smoking and drinking will cause serious harm to men, mainly including diseases of the respiratory system, cardiovascular and cerebrovascular system, genitourinary system and digestive system. 1. Diseases of the respiratory system: Smoking can cause serious damage to the respiratory system, resulting in chronic obstructive pulmonary disease, chronic bronchitis, lung cancer and so on. 2. Cardiovascular diseases: smoking and drinking will induce cardiovascular diseases. Cigarettes contain nicotine, nicotine and other harmful substances, which will damage the endothelium of the blood vessels, thus inducing vasospasm or plaque, and may also cause angina pectoris, hypertension, coronary artery disease, myocardial infarction, cerebral hemorrhage, cerebral infarction and so on. 3. Genitourinary diseases: Smoking and drinking may lead to prostate diseases, affecting the sperm’s ability to move, leading to infertility. 4. Diseases of digestive system: people who abuse alcohol for a long time may develop gastric ulcer, gastric cancer, chronic gastritis, cirrhosis of the liver, liver cancer and other diseases. Therefore, male friends should pay attention to quit smoking and drinking to avoid diseases that jeopardize their health.