Drooling in middle-aged and old people is usually treated with medication according to different causes, such as due to cerebrovascular disease, can be given according to different cerebrovascular diseases such as antiplatelet, dehydration, nutritive nerve medication or surgical treatment; peripheral neuropathy caused by, can take nutritive nerve medication; oral ulcers caused by, can be used externally in the treatment of bulk. 1. Cerebrovascular disease: it may be due to cerebral atherosclerosis and occlusion caused by cerebral infarction, or cerebral hemorrhage, etc. In addition to drooling, there may also be impaired consciousness and hemiparesis. For cerebral infarction, anti-platelet drugs such as aspirin and lipid-lowering drugs such as Rosuvastatin can be taken under doctor’s guidance. For cerebral hemorrhage, drugs such as mannitol and furosemide should be given intravenously in general, and nutritive neurological drugs such as cytarabine injection can be given at the same time. In serious cases, surgery is needed. 2. Peripheral neuropathy: Facial neuritis, for example, can also lead to drooling symptoms. It can be treated with nerve-nourishing drugs such as glutamine and methylcobalamin tablets under the guidance of a doctor. Acupuncture and other treatments can also be used by a medical professional. 3. Mouth ulcers: usually caused by irritation of the oral mucosa or caused by too hard food, there will be bad breath, redness, swelling, pain and drooling of the oral mucosa. It can be treated with ice boron powder and mouth ulcer powder under doctor’s guidance. Drooling in middle-aged and old age should be treated systematically under the guidance of a doctor according to the cause of the disease.