Oral application of iodized glycerin is generally not used for the treatment of oral leukoplakia, and the latter can be relieved by drugs, laser and surgical treatment according to the situation. 1. Iodized glycerin is a kind of disinfectant and antiseptic for local use in oral cavity only, it has killing effect on bacteria, fungi and viruses, and it is suitable to be used in the treatment of oral mucous membrane ulcers, gingivitis and pericoronitis, and it is generally not used in the treatment of oral leukoplakia. It should be prohibited for those who are allergic to the product, used with caution in newborns, and the adverse reaction of allergic reaction is occasionally seen during the use of the drug. 2. Oral leukoplakia refers to white spots of oral mucosa, there is no cure at present, it is suggested to eliminate local stimulating factors (such as quitting smoking and alcohol, avoiding betel nut chewing, etc.), medication (such as vitamin A acid, vitamin E, etc.), laser treatment (carbon dioxide laser, etc.), and regular follow up to prevent cancerous changes, if there is a tendency of cancerous changes, it can be rechecked once every 3-6 weeks, and surgery can be taken if necessary. Specific medication should be administered under the guidance of specialized physicians.