Patients with coronary heart disease should avoid taking drugs that can cause increased heart rate and blood pressure. Coronary heart disease is known as coronary atherosclerotic heart disease, the main reason is that the coronary artery lining lipid deposition to form different degrees of plaque, these plaques gradually increase to make the arterial lumen narrowed, the blood circulation flow is blocked, thus leading to myocardial ischemia. Any drug that causes an increase in heart rate, such as aminophylline, salbutamol, and any drug that causes an increase in blood pressure, such as norepinephrine and dopamine, will lead to an increase in myocardial oxygen consumption, thus aggravating myocardial ischemia in patients with coronary artery disease, and the use of these drugs is prohibited. Coronary artery disease patients need to be under the guidance of the doctor reasonable use of drugs, usually choose nitrate such as nitroglycerin, β-blockers such as metoprolol, calcium channel blockers such as nifedipine, antiplatelet agents such as aspirin, statin lipid-lowering drugs such as lovastatin, and if the condition is serious need to be carried out coronary artery bypass grafting surgery. Usually, we should also pay attention to reasonable work and rest, appropriate exercise, light diet, quit smoking and limit alcohol, maintain physical and mental health, and reasonable use of medication under the guidance of the doctor.