Lower back pain can be caused by a variety of reasons and should be treated. Common causes include physiological causes such as sprains and strains of the low back muscles, and pathological causes such as herniated lumbar discs and autoimmune diseases such as ankylosing spondylitis. Treatment includes general treatment, medication, physical therapy and surgery. 1. Physiological causes: mostly due to heavy physical labor, poor posture and other causes of lumbar back muscle sprains, strains, strain, manifested as lumbar pain, or even can not walk, usually after resting for a period of time the symptoms can be relieved. 2. Lumbar disc herniation: Lumbar disc herniation can compress the nerves, manifested as lumbar pain, accompanied by leg numbness, sciatica and other symptoms. Light condition can be treated conservatively, taking non-steroidal anti-inflammatory drugs such as ibuprofen and other anti-inflammatory analgesic, at the same time with lumbar traction and acupuncture, massage, massage and other physical therapy, the more serious condition can be selected for nucleus pulposus removal and other surgical treatment. 3. Autoimmune diseases: common ankylosing spondylitis, which can be manifested as lumbar pain, or even inability to walk, usually aggravated in the morning, and will be alleviated after activities. Therapeutic drugs include non-steroidal anti-inflammatory drugs, anti-tumor necrosis factor α antagonists such as enalapril, anti-rheumatic drugs such as lorazosulfapyridine. Lumbar pain can also be seen in other causes such as tumor lumbar metastasis, lumbar spine tuberculosis infection and other reasons, it is recommended to exclude physiological causes, timely to the hospital, clear cause and timely treatment, the above drugs should be used under the guidance of a doctor.