Facial allergies are not recommended to use erythromycin ointment, can not achieve the therapeutic effect, should follow the doctor’s instructions for medication. Facial allergy is an abnormal immune response caused by allergens that enter the body through skin and mucous membrane contact. The treatment needs to remove the allergens, the use of anti-allergy drugs such as loratadine, cetirizine and other treatments. Erythromycin ointment belongs to the topical antibiotic, with antibacterial effect, used for small burns, purulent dermatosis, infection of ulcerated surfaces, common acne and so on. Adverse reactions are seen as irritation, allergic reactions. It is contraindicated for those who are allergic to the product. Therefore, the use of erythromycin ointment for allergies on the face is not recommended and does not play a therapeutic role. Reasonable anti-allergy treatment should be carried out under medical supervision.