Clothes that have been crawled on by rats and not washed and worn by rat fleas may be infected with bubonic plague; however, it is possible to continue to wear the clothes after they have been sterilized. Bubonic plague is an infectious disease caused by Yersinia pestis, which is transmitted between rats and humans through the medium of rat fleas, which bite rats suffering from bubonic plague, and then cause infections in healthy people after biting them. If a rat crawls over clothes and fleas remain on the clothes, and a person is bitten by fleas after wearing them, he or she may be infected with the plague. Bubonic plague is a category A infectious disease and is now relatively rare. If there is an outbreak of plague in your place of residence, the CDC and other relevant departments will usually conduct publicity and exterminate rats. If you are worried about contamination of clothes crawled by rats, you can disinfect your clothes and put them in the sun to kill bacteria and rat fleas.