At present, there are many reasons for cranial defects in life. Due to the lack of cranial protection, the dura mater is in direct contact with the skin and so on, resulting in local collapse or bulge, which is easy to be squeezed, collision and so on causing cranial injury, which brings inconvenience to the work and life of patients. Therefore, when patients have cranial injury, they should have cranial repair surgery as soon as possible. Broadly speaking, there are risks and dangers whenever surgery is done, but the danger of cranial repair is very low, and there are two main risks faced in the short term, bleeding and infection, which are directly related to cranial repair. Bleeding is usually less than 3 days and if it is more than 3 days the chances of further bleeding will be minimal. The likelihood of infection is generally no more than 10 days, and if it does not occur 10 days after cranial repair, the likelihood of infection is becoming less and less likely. At present, the skull repair material widely used in most hospitals is titanium mesh material, but this material also has certain defects, such as postoperative infection rejection phenomenon, hot and cold sensitive reaction phenomenon, easy to deformation by force, affecting ct nuclear magnetic examination and so on. The peek material is a new type of special polymer material with excellent performance, which overcomes the various problems that may arise with titanium mesh material and can be used in cranial repair to achieve excellent repair results. Through clinical practice, PEEK was found to be low-density, insensitive to temperature, and has high tissue stability, allowing it to be sterilized at high temperatures or under radiation without deformation. And through a large number of clinical feedback found that PEEK material has radiation permeability, CT and MRI results will not have an impact. PEEK cranial repair surgery, this surgery not only achieves a single cranial repair, but also puts a great deal of effort into cosmetic surgery, conducting scientific analysis and research on each patient’s specific condition and signs, optimizing the design of the repair material, and developing a personalized and thorough cranial repair and cosmetic surgery plan, ultimately achieving a unified appearance, anatomical integrity, and functional perfection.