Shingles on the legs in adults is caused by varicella-zoster virus infection. Varicella-zoster virus is the common pathogen that causes chickenpox and shingles; the primary infection manifests as chickenpox, and reactivation of the virus latent in nerve cells causes shingles. The main symptoms of shingles are a rash and neuralgia. The rash is a series of blisters distributed along the peripheral nerves of the thighs, usually not exceeding the midline. The blisters are in the form of bands, some of which may rupture and become infected, producing an inflammatory response. Severe neuralgia may be present in the area of distribution of herpes zoster on the thigh, and this pain is persistent or paroxysmal stabbing, pinching, or burning pain. Symptoms are especially pronounced in older patients and can even cause postherpetic neuralgia in some cases after the rash has subsided. When herpes zoster appears, seek medical treatment in time. Normally, you should actively participate in physical exercise to enhance physical fitness. Avoid overwork, try not to contact the chemical substances that harm the skin. At the same time, you should strengthen nutrition to enhance the body’s resistance.