IgA nephropathy stage III creatinine 186μmol/L is generally not curable, but with proper treatment, the clinical symptoms can be relieved. IgA nephropathy pathology is divided into 5 stages, stage I tiny lesions, stage II mild lesions, stage III focal segmental glomerulonephritis, grade IV diffuse thylakoid proliferative nephritis, and stage V diffuse sclerosing glomerulonephritis, among which stage III of IgA nephropathy is generally irreversible changes. Symptoms such as hematuria, proteinuria, hypertension and renal insufficiency will occur. The normal level of blood creatinine is 53~106 μmol/l for male reference value, 44~97 μmol/L for female reference value , the standard value of each hospital is different, you can test the reference value according to the local hospital. When creatinine 186 μmol / L when the kidney function is obviously impaired. The current treatment can only relieve the symptoms and slow down the deterioration of the disease. For the treatment of IgA nephropathy stage III creatinine 186 μmol/L, the main thing is to ensure a low-salt, low-fat, low-sugar diet, moderate supplementation of high-quality proteins; choose prednisone, cyclophosphamide, valsartan, Benadryl, hydroxychloroquine and other drugs for treatment, try to reduce the urinary protein, blood creatinine, and slow down the disease progression. The above medications need to be under the guidance of physicians, and should not be used without authorization. Patients with IgA nephropathy are recommended to consult regular hospitals in time and standardize the treatment under the guidance of physicians.