Pain occurs at the junction of the toes and the ball of the foot for several common reasons: First, metatarsalgia, where the patient experiences severe strain on the transverse arch of the forefoot, causing local pain. Female patients who wear high heels, which overly concentrate the weight on the forefoot, can also cause pain. After the patient has metatarsalgia, there will be severe pain, limited movement, and will be accompanied by local swelling, increased skin temperature, the pain symptoms disappear after the foot is lifted, and can produce callus on the bottom of the foot. Second, trauma, in the process of movement, acute injury can occur to the joints of the toes and metatarsals, the patient will have local symptoms of severe pain, and sometimes a fracture or even dislocation can occur, the pain will be more pronounced, the patient can not carry weight bearing, and can not carry out activities. Therefore, when pain occurs in this area, it should be diagnosed and treated promptly.