Thyroid puncture can be observed for at least 30 minutes after the procedure to rule out complications such as active bleeding and respiratory distress, but care should be taken to avoid strenuous neck activities, etc. Thyroid cytocentesis biopsy can identify the nature of thyroid nodules before surgery, which provides the basis for individualized and precise treatment of thyroid diseases, and is the key to the decision of thyroid diagnosis and treatment. It is important to observe the patient for at least 30 minutes after the puncture to rule out complications such as bleeding and severe pain. In addition, after leaving, care should be taken to avoid diets and medications that increase the risk of bleeding; strenuous neck activity should be prohibited; and care should be taken to follow up on pathologic test results. If there is any neck swelling, increased pain, or difficulty in breathing, it is necessary to inform the physician or go to the hospital promptly.