Very low density lipoprotein is a hepatically synthesized lipoprotein composed of cholesterol, triglycerides and protein and is primarily influenced by triglycerides, dietary structure and metabolism. Elevation of very low density lipoprotein is often accompanied by elevated triglycerides and is also associated with coronary heart disease such as pancreatitis and type 2 diabetes. Moreover, very low density lipoprotein can be converted into low density lipoprotein, so it is believed that very low density lipoprotein is closely related to atherosclerosis and is also a factor of atherogenesis, which can be used to reflect the chance of atherosclerosis. Therefore, if elevated VLDL is found to be accompanied by elevated triglycerides, oral lipid-lowering drugs should be taken promptly under the guidance of a cardiologist.