Immunopneumonia, which is also known as immune-associated pneumonia, may present with fever, cough, sputum, chest pain, dyspnea, etc. The mechanism of its occurrence is not yet known, but most scholars believe that it may be related to excessive activation of the immune system. Immuno-associated pneumonia can be divided into autoimmune-associated pneumonia and immune checkpoint inhibitor-induced immune-associated pneumonia, the mechanism of which has not yet been clarified, but most scholars believe that it may be related to the over-activation of the immune system. Immunopneumonia is most common in interstitial pneumonitis, with new or worsening dyspnea, hypoxemia, and cough as the main clinical manifestations, and some patients may have sputum, chest pain, hemoptysis, fever, and malaise, etc. Some patients may have Raynaud’s phenomenon and finger swelling characterized by primary immune disease, and about one-third of them may have no symptoms at the time of the onset of the disease. Immunopneumonia is a rare but highly fatal disease, and should be diagnosed and treated promptly once it is detected.