In patients with skin melanosis, there are usually no conscious symptoms and only limited or diffuse skin pigmentation. The causes of skin melanosis are complex and may be related to malnutrition, endocrine disorders, friction, and exposure to photosensitizing substances. There are no self-conscious symptoms, and common lesions show localized grayish-purple hyperpigmented patches of skin, and some patients may have rough skin. The disease is a benign reversible lesion. Patients can follow the doctor’s instructions in the skin local application of hydroquinone cream or dexamethasone and other glucocorticoid drugs for treatment, but also oral multivitamins and other drugs to promote the recovery of the lesions. In general, patients in active cooperation with the treatment to eliminate the causative factors, the prognosis is relatively good, usually to maintain good habits, pay attention to do a good job of skin moisturizing and sunscreen measures, so as not to lead to recurrence or aggravation of the disease.