Pain in the incision is a normal manifestation during dressing changes. In order to alleviate the pain experienced by the patient, the first step should be to operate gently, and the removal of gauze should also be carefully avoided to cause local skin damage. In addition, for patients with large wounds, especially open heart surgery patients, at the end of the operation can be in the intercostal nerve for local closure, injection of lidocaine hydrochloride can significantly reduce the patient’s local wound pain, but also conducive to the operation of the operation after the change of medication. For patients with severe pain, such as perianal disease, you can choose to take oral pain medication, after the effect of the drug to carry out local drug change, but also in the change of drugs before the first local saline sitz bath, or in the trauma of spraying lidocaine or the application of lidocaine gel, can reduce the patient’s pain symptoms.