Lupus erythematosus nephritis may develop into chronic renal failure if not treated in time, which may threaten patients’ life, but the prognosis of patients can be improved through standardized treatment. Lupus erythematosus nephritis is a kidney damage caused by systemic lupus erythematosus, patients often have intermittent fever, erythema, hematuria, proteinuria and other symptoms. If the disease is not treated in time, the condition may gradually progress to chronic renal failure, and in the late stage, it may develop to uremia, and even threaten the patients’ life and health. The treatment of lupus erythematosus nephritis includes medication and renal replacement therapy, etc. Through standardized and timely treatment, it can protect patients’ renal function, prevent recurrence of the disease and improve the prognosis of lupus erythematosus nephritis patients, and the survival rate of lupus erythematosus nephritis patients in 10 years after the treatment is 80%～90%. It is recommended that patients with lupus erythematosus nephritis should go to regular hospitals for further examination under the guidance of specialists and actively cooperate with the treatment, so as to avoid delaying the condition.