Age-related macular degeneration (AMD) occurs in almost all of us in our middle and old age. However, most of them have no significant impact on vision and life. Only some of them have rapid progression and short-term aggravation, which have serious impact on vision, so we need early detection, early diagnosis, early treatment, and control the disease in the least damaging stage. Age-related macular degeneration (AMD), generally divided into dry and wet, dry AMD mostly occurs in older people over 50 years old, symmetrical in both eyes, vision is extremely slow progressive decline, patients often have no obvious symptoms, some have vision loss, visual distortion and other symptoms. On fundus examination, there is pigment disorder in the macular area of both eyes, the central concave light reflection disappears, and some yellowish-white vitreous warts of different sizes and not very clear borders can be seen in the posterior pole from time to time. In some patients, due to the atrophy and pigment loss of the retinal pigment epithelium, a map-like atrophy area with clear borders can be seen in the posterior pole of the retina. If the choroidal capillaries are also atrophic, some thick choroidal vessels can be seen in the atrophic area. Wet AMD is due to the formation of choroidal neovascularization when the lesion is further aggravated. once CNV is formed, it will cause a series of pathological changes such as exudation, hemorrhage, mechanization and scarring due to the structural imperfection of the neovascularization, which will eventually lead to the loss of central vision. Wet AMD mostly occurs in elderly people over 60 years of age, with one eye developing first and the contralateral eye may develop after a considerable period of time, but there are a few patients with simultaneous or sequential onset in both eyes. Unlike dry AMD, which is characterized by a slow progressive decline in vision, patients with wet AMD have a rapid onset of vision loss and visual distortion, which is often apparent within a short period of time. Funduscopic examination reveals that the lesions in the posterior pole of the fundus have become very extensive, and extensive lesions are never formed within a short period of time. Because the lesion occurs in the posterior pole, but the lesion has not yet affected the central recess, many patients do not notice the symptoms, and only once the lesion invades the central recess and the central vision is impaired will the patient notice the vision loss. Therefore, middle-aged people should regularly check the fundus, especially when there is vision loss and visual distortion, if the lesion is treated relatively well at an early stage, but at an advanced stage the treatment is expensive and ineffective.