Azoospermia is a common cause of male infertility and a cause of absolute male sterility. For azoospermia, specific analysis should be made for specific problems to determine whether it is obstructive azoospermia or non-obstructive azoospermia. The details are as follows: 1. For obstructive azoospermia: the vas deferens can be reconstructed surgically so that it is unobstructed and the sperm can be discharged during sex, i.e., natural conception can be achieved through conjugal life; in addition, IVF can also be chosen to achieve pregnancy through single sperm follicular plasma microinjection for fertility. Some patients can be treated surgically and surgery should be considered first; in cases where surgical treatment does not achieve the goal, IVF can be chosen. For some patients, the cause of obstruction is congenital, for such patients it is not necessary and impossible to achieve fertility through surgery, and IVF technology should be chosen in one step; 2. For non-obstructive azoospermia: it can be divided into low-promoting and high-promoting azoospermia, low-promoting-related non-obstructive azoospermia can be treated by medication to improve the symptoms through medication and then achieve fertility through conjugal life For patients with non-obstructive azoospermia with high azoospermia, there are more treatment methods, but the results are average. For patients with non-obstructive azoospermia who want to obtain their own genetic offspring, microscopic sperm retrieval is currently the main technique. The combination of microscopic sperm retrieval techniques to obtain sperm and IVF techniques can be used to obtain their own genetic offspring.