There are numerous factors that affect an elevated red blood cell count in urine tests, such as abnormal coagulation or thrombocytopenia, which can lead to an increased probability of mucosal bleeding, when there is a significant increase in the number of red blood cells in the urine. Trauma to the urinary system may result in an increased red blood cell count, such as trauma to the lower back, lower abdomen, or genitalia outside the urethra, which can cause a high red blood cell count. Infections, stones, tumors and other diseases of the urinary system can lead to abnormal red blood cells in urine, and these diseases can lead to rupture and bleeding of the mucous membrane of the urinary tract, or necrosis and bleeding, which can lead to an increase in the number of red blood cells in urine, or even to the occurrence of hematuria. High erythrocyte count in urine may also occur in various types of nephritis; high erythrocyte count in urine may also occur in cases of major trauma, such as crush injury or extensive injury.