Lymphoma is a hematologic disease and one of the common malignant tumors of the head and neck. Lymphoma of head and neck often affects lymph nodes of head and neck, nasal cavity, oral cavity, pharynx, paranasal sinus, orbit, skull base and soft tissues of face, etc. It may present with various clinical manifestations such as headache, nasal congestion, pus and blood snot, nasal swelling, enlarged and ulcerated tonsils, hoarseness, protruding eyes, diplopia, facial swelling, neck mass, fever, emaciation and night sweats. Head and neck lymphoma invades complex structures and has various pathological types, and scientific and standardized diagnosis and treatment require multidisciplinary participation.