The most effective way to relieve the headache after drinking alcohol is as follows: First, non-steroidal anti-inflammatory drugs can be applied, such as antipyretic and analgesic drugs, the drugs that can be applied are ibuprofen extended-release, indomethacin, aminosalicylic acid and compound aminobarbital drugs, typical drugs such as somitol, ibuprofen and fenbid can relieve the headache. Second, can apply rapid decomposition of alcohol drugs, can also decompose the headache produced by alcohol, such as injection of naloxone hydrochloride, injectable vitamin C can quickly decompose alcohol, the effect of decomposition of alcohol to relieve headache. Third, ice and cold compresses can be applied, and ice towels or ice cubes can be applied for 10-15 minutes along the arch of the eyebrows, frontal bone to the back of the head and temples to relieve dizziness and headache. Fourth, if the symptoms of the appeal do not ease, you can go to the hospital to perform physical therapy, the application of microwave physiotherapy instrument can relieve the headache.