The difference between rheumatoid and gout lies in the pathogenesis, symptoms and treatment. 1. Pathogenesis: Gout is a metabolic disease caused by the deposition and aggregation of urate crystals in the joints and surrounding soft tissues of the patient, which is a metabolic disease; rheumatoid arthritis has not yet been clarified, and is now mainly considered to be an autoimmune disease, which is related to immune function disorders. 2. Symptoms: the main symptom of gout attack is red, swollen, hot and painful joints, with severe pain, and there is no obvious symptom during the remission period, and there may be gout stone formation, which often involves a single joint. Common clinical symptoms of rheumatoid arthritis include morning stiffness, joint swelling and joint pain, etc. With the progress of the disease, there will be joint deformity, mostly symmetrical small joint involvement. 3. Treatment: Gout treatment is based on uric acid-lowering drugs such as benzbromarone, colchicine and non-steroidal anti-inflammatory drugs such as diclofenac, while rheumatoid arthritis treatment is based on anti-rheumatic drugs such as cyclophosphamide, non-steroidal anti-inflammatory drugs such as celecoxib and other drugs, and surgical treatment should be taken if necessary. The drugs should be used according to the doctor’s prescription. It is recommended that patients go to the rheumatology and immunology department of regular hospitals, orthopedics and other related departments for detailed consultation, and follow the doctor’s instructions for treatment.