Itchy toes with small blisters are most commonly associated with tinea pedis, but there is also the possibility of eczema as well as sweating herpes. Tinea pedis is caused by superficial fungal infections, blistering tinea pedis will have blisters on the toes, blisters will be accompanied by collar-like flaking after drying, because of the contagious, the scope will gradually expand. In the treatment can be applied antifungal ointment, such as terbinafine ointment or sertaconazole nitrate cream, need to insist on applying 4-6 weeks can subside. Eczema is an allergic disease related to a variety of internal and external factors interacting with each other, will be symmetrically distributed in the two toes erythema, blisters, accompanied by itching, need to be anti-allergy treatment, such as applying mometasone furoate ointment or butyl flufenamic acid ointment. Sweat herpes belongs to a special type of eczema, the main manifestation is the appearance of deep blisters on both feet, there is obvious seasonal, treatment with the same medication as eczema.