After a stent is placed in a three-branch diffuse lesion of the coronary artery, it can usually be used all the way through if no stenosis or blockage of the blood vessel occurs. Three-branch diffuse lesions of the coronary arteries refer to lesions in all three major coronary vessels, which are the anterior descending branch of the left coronary artery, the circumflex branch of the left coronary artery, and the right coronary artery. When a patient is placed in a stent, antiplatelet coagulation medications are needed to prevent the vessel from becoming blocked again. Generally, if it is well controlled and the vessel is not narrowed or blocked again, the stent can be used all the time. However, if any of the above situations occurs, it should be replaced in time, therefore, there is no exact time for how long it will last. Patients are advised to follow the doctor’s instructions for review to determine the condition of the blood vessels. Maintain a healthy and regular lifestyle to avoid aggravation of the condition.