Preventive measures must be taken during the high season of HFMD. The first is to wash children’s hands with soap or hand sanitizer before meals, after defecation, and after going out, and not to let children drink raw water or eat cold food to avoid contact with sick children. Secondly, caregivers should wash their hands before touching children, changing diapers and handling feces, and properly dispose of dirt. Third, bottles and pacifiers used by infants should be washed well before and after use. Fourth, during the epidemic period, do not take children to public places where people gather and air circulation is poor, and pay attention to keeping the home environment sanitary, ventilating the living room frequently and drying clothes and blankets. If children develop symptoms, they should go to a medical institution in time and should not come into contact with other children. Parents should promptly dry or disinfect the child’s clothes and disinfect the child’s feces. Children with mild cases do not need to be hospitalized and should be treated and rested at home to reduce cross-infection. Wash and disinfect toys, personal hygiene products, dishes and other items daily. If a child is present in the same kindergarten, it is necessary to give the child a short break and try not to go to places where there are many affected children.