Routine urine protein (+-) is a weak positive urine protein, 0.15 is the meaning of 0.15g, which is the threshold value of urine protein. If urine protein <0.15g is considered negative for urine protein, generally no special treatment is needed, if urine protein >0.15g is considered positive for urine protein, it is divided into two cases: functional proteinuria and pathological proteinuria. Functional proteinuria is mostly affected by fever, cold, strenuous exercise, or cold, etc. It does not need special treatment and can return to normal after these influencing factors are removed. If urine protein continues to be positive, pathological proteinuria is considered, which is seen in acute and chronic nephritis, nephrotic syndrome and various secondary nephropathies, etc. We need to do a 24h urine protein quantification test and treat according to the 24h urine protein quantification. If it is a small amount of proteinuria, it can be treated with ACEI or ARB drugs, if it is a large amount of proteinuria or moderate amount of proteinuria, it can be treated with hormones combined with cytotoxic drugs.