Nails with vertical stripes, no crescent moon may be a normal physiological phenomenon, may also be due to malnutrition, nail moles and other disease factors, and there is no necessary connection between the two symptoms. 1. Normal physiological phenomenon: vertical lines on the nails are formed in the process of the nails on the body, many healthy people will exist in the distribution of uniform, and normal color vertical stripes, generally long-term persistence, no obvious changes; crescent called “half-moon mark”, is the growth of the nails, the size, whether or not it varies from person to person, and is usually not directly related to the physical health condition. Its size and presence vary from person to person, and usually have no direct relationship with the health condition of the body. 2. Malnutrition: When vertical lines appear on the nails within a short period of time, accompanied by changes in nail color, brittle texture and easy to crack, it may be caused by malnutrition, such as a lack of calcium, zinc and other micronutrients; on the other hand, malnutrition can also lead to slow metabolism, resulting in the gradual disappearance of half-moon scars. 3. Onychomycosis: Onychomycosis is mainly manifested by the blackening of nails and the appearance of black bands with clear boundaries, and the depth of its color may be related to the amount of melanin produced by the nevus cells in the onychomycosis region. 4. Other diseases: psoriasis, lichen planus, eczema and other skin diseases may lead to blurred boundaries or disappearance of the meniscus; suffering from liver failure, renal failure, nail bed tumors and other diseases may also lead to the disappearance of the meniscus. It is recommended that people who have vertical lines on their nails and no crescent moon, when in doubt or when there are obvious changes in a short period of time, it is recommended that they consult a doctor in a timely manner in order to clarify the cause of the disease and to carry out targeted treatment.