General treatment, topical medication, and systemic medication can be given for prickly heat on the neck Prickly heat is due to the external temperature is too high, sweat is not easy to evaporate, resulting in the stratum corneum infiltration, swelling, causing sweat ducts become narrow or blocked. 1. General treatment: keep the skin clean and hygienic, avoid living and working in a hot environment again, choose loose and soft clothes. 2. Topical medication: use glycerin lotion, prickly heat powder, etc. If you have pus rash, you can choose ichthyol ointment, Huanglian powder, etc. 3. Systemic medication: you can take antihistamines such as loratadine and cetirizine for obvious itching, and amoxicillin and cefadroxil for serious infections. Prickly heat on the neck, it is recommended to go to the regular medical institutions in a timely manner, in accordance with the specialist medical advice standardized treatment, to avoid blind self-medication, so as not to cause adverse consequences.