How long the life span of invasive lobular carcinoma of breast is generally related to the clinical staging and molecular staging of the tumor and the physical status score of the patient. 1. Clinical staging: if invasive lobular carcinoma is in the early stage of the disease, without lymph node metastasis and invasion of distant tissues and organs, the 5-year survival rate of the patients after surgical treatment is high, generally up to more than 80%. If the disease is in advanced stage and metastasis has occurred, the 5-year survival rate is lower. 2. Molecular typing: if invasive lobular carcinoma is triple-negative breast cancer by genetic test, the survival period of patients is relatively shorter, the 5-year survival rate is relatively low, and the prognosis is poor. 3. Patient physical status score: the higher the ECOG score, the lower the KPS score, the worse the patient’s general condition, the shorter the survival period; on the contrary, the survival period is longer. Early diagnosis and early treatment are needed for invasive lobular carcinoma.