The first thing to do is to distinguish between physiological and pathological jaundice. Physiological jaundice does not require treatment, and will subside on its own within two weeks in full-term infants, and not more than four weeks in preterm infants. If the jaundice is pathological, hospitalization is required. Depending on the severity of the jaundice, blue light irradiation is chosen, and albumin is applied intravenously to reduce free bilirubin. If the jaundice is hemolytic, intravenous gammaglobulin is needed to block hemolysis, and severe pathological jaundice requires blood exchange. If the child’s jaundice lasts for a long time and is combined with impairment of liver function, this condition is called infantile hepatitis syndrome. Further search for the cause of the disease is needed, and according to the different causes, different treatments are adopted.