Cleanliness is a kind of obsessive-compulsive disorder, which can be treated by general therapy (relaxation, etc.), psychotherapy (cognitive therapy, etc.) and medication (fluvoxamine tablets, etc.), and its treatment varies according to the degree of the disease. 1. General treatment: For mild cleanliness fetishism, the patient is to eliminate the fear of being contaminated by dirt, poison and bacteria, and repeatedly wash hands and lock the door, and so on. Generally, the abnormal phenomena brought about by cleanliness can be relieved by relaxing emotions, trusting one’s intuition, not bothering about the reality of things, and maintaining sufficient sleep to relieve tension. 2. Psychotherapy: If the cleanliness fetish is more serious, extreme obsessive-compulsive disorder, excessive nervous tension, etc., can follow the doctor’s instructions for supportive psychotherapy, cognitive therapy, behavioral therapy or desensitization therapy and other psychological therapies. Can change the patient’s cognition of abnormal behavioral habits, through negative feedback and other treatments to alleviate the cleanliness. 3. Drug therapy: If necessary, oral fluvoxamine maleate tablets, paroxetine hydrochloride tablets, sertraline hydrochloride tablets and other drugs can be prescribed to lift the abnormal transmission of nerves, which can usually alleviate cleanliness to a certain extent. Liver and kidney functions should be closely monitored during the course of the medication, and it is contraindicated in allergic cases. Therefore, if you are suffering from a cleanliness fetish, the doctor will choose a different way of treatment according to the patient’s situation, due to individual differences in the situation, specific case-by-case treatment, in order to avoid delays in the condition, it is recommended to go to the hospital in a timely manner to clarify the condition of the situation and give standardized treatment.